The new-look newsfeed has given more space to music, games and advertising and attempts to reduces clutter as the company aims to boost profits.
Photographs, check-ins and other updates appear larger on the new design which features a new left hand navigation bar and separate tabs for music and games.
With the new design, photographs will now account for 50 per cent of the content on the news feed. It was 25 per cent in November 2011.
Zuckerberg said: “The design of your news feed needs to reflect the evolving face of who you’re sharing with”.
Facebook has also announced the new design means the social network will look the same for smartphones, tablets and online users.
Ian Maude, an internet analyst at Enders Analysis, told the Guardian the news feed advertising is where Facebook has its most success in both mobile and desktop.
He said: “The trick is going to be managing the volume of ads people see in the news feed and getting the balance right between maximising revenue, but also keeping users happy.